Droperidol
Is frequently used in the treatment of ambulatory patients. It can reduce nausea and vomiting by action on the CTZ.
Dose: 0.625 – 1.25 mg IV
Onset: 3- 10 minutes
Peak Action: 30 minutes
Duration: 2-4 hours
Potential Adverse Reactions:
- Mild to moderate hypotension
- Drowsiness and prolonged recovery when given in larger doses.
Compazine (Prochorperazine)
Dose: 5 – 10 mg IV or deep IM
Administration Technique: Begin with lowest recommended dose. No more than 5 mg/minute IV. Maximum dose of 10 mg IV.
Potential Adverse Reactions: Drowsiness, dizziness
Phenergan (Promethazine)
Dose: 12.5 – 25 mg IV or 25-50 mg IM
Onset: 20 minutes
Peak Action: 4-6 hours
Duration: Up to 12 hours
Potential Adverse Reactions: Drowsiness, dry mouth.
Zofran (Ondansetron Hydrochloride)
Dose: 4 mg IV over 2-5 minutes
Onset: 20 minutes
Peak Action: 3.5 hours
Duration: Up to 8 hours
Potential Adverse Reactions: Minimal side effects